AICH Roma - newshd.net - newsletters 18 mag. 2016

NEWSLETTERS - The Huntington's Disease News
By AICH - Roma Onlus

Newsletters 18 mag. 2016

Huntington's disease news

www.newshd.net

Mag. 4 2016
Toward a Salivary Biomarker for Huntington Disease
Dr Corey-Bloom: Our overall motivation was to try and identify peripheral biomarkers for HD. In this study, we were specifically trying to assess whether salivary Htt levels can serve as a biomarker for HD and disease burden.

Mag. 17 2016
Unravelling the genetic secrets of Huntington’s disease
One of Monash University’s doctorate students, April Philpott, was a finalist in the Victorian Young Achiever’s Awards. April undertook her PhD in the Experimental Neuropsychology Research Unit, School of Psychological Sciences, headed by Professor Nellie Georgiou-Karistianis.

Mag 17 2016
Using exercise to reduce glutamate build-up in the brain
New research shows that exercise could reduce symptoms of neurodegenerative diseases such as Huntington’s disease

Mag. 14 2016
New study suggests rethink of dementia causes
University of Adelaide researchers have developed a new theory for the causes of dementia and other neurodegenerative diseases, involving an out-of-control immune system.

13 mag. 2016
Huntington’s Disease target of $4.5 million in NIH grants
Huntington’s Disease is a devastating, fatal, inherited disease that causes nerve cells in the brain to break down over time, and there is no cure.

Mag. 5 2016
On the Hunt for Huntington’s Disease Treatments in the New Millennium
This bold and inspiring statement was made by Dr. Ray Dorsey at the inaugural HD-CAREsymposium for Huntington’s disease (HD) research held at UC Irvine last month. The event brought together scientists, doctors, patients, family members..

Mag. 03 2016
Important drug targets yielded by new genetic study of HD
A genetic study confirms that minute differences in DNA repair genes can influence the age of HD symptom onset.

ARTICLES SCIENTIFIC

An introduction to implementation science for the non-specialist.

Structural basis for the substrate selectivity of PvuRts1I, a 5-hydroxymethylcytosine DNA restriction endonuclease.

Poly-glutamine expanded huntingtin dramatically alters the genome wide binding of HSF1.

Genetic Deficiency of Complement Component 3 Does Not Alter Disease Progression in a Mouse Model of Huntington's Disease.

Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice.

ABSTRACT

Exosomes from adipose-derived stem cells ameliorate Huntington's disease phenotypes in an in vitro model.

Exosomes from adipose-derived stem cells ameliorate Huntington's disease phenotypes in an in vitro model. Eur J Neurosci. 2016 May 14; Authors: Lee M, Tian L, Im W, Kim M Abstract Huntington's disease (HD) is a hereditary...

Genetic counseling and testing for Huntington's disease: A historical review.

Genetic counseling and testing for Huntington's disease: A historical review. Am J Med Genet B Neuropsychiatr Genet. 2016 May 13; Authors: Nance MA Abstract This manuscript describes the ways in which genetic counseling h...

Epigenetic Regulation of Virulence Gene Expression in Parasitic Protozoa.

Epigenetic Regulation of Virulence Gene Expression in Parasitic Protozoa. Cell Host Microbe. 2016 May 11;19(5):629-40 Authors: Duraisingh MT, Horn D Abstract Protozoan parasites colonize numerous metazoan hosts and insect vector...

Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015).

Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015). Expert Opin Ther Pat. 2016 May 12; Authors: Zádori D, Veres G, Szalárdy L, Klivényi P, Fülöp F, Toldi J, Vécsei L Abstract INTRODUCT...

RNA-Seq of Huntington's Disease Patient Myeloid Cells Reveals Innate Transcriptional Dysregulation Associated With Proinflammatory Pathway Activation.

RNA-Seq of Huntington's Disease Patient Myeloid Cells Reveals Innate Transcriptional Dysregulation Associated With Proinflammatory Pathway Activation. Hum Mol Genet. 2016 May 11; Authors: Miller JR, Lo KK, Andre R, Moss DJ,...

Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions.

Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions. Biochim Biophys Acta. 2016 May 8; Authors: Diaz-Hidalgo L, Altuntas S, Rossin F, D'Eletto M, Marsella C,...

An introduction to implementation science for the non-specialist.

Related Articles An introduction to implementation science for the non-specialist. BMC Psychol. 2015;3:32 Authors: Bauer MS, Damschroder L, Hagedorn H, Smith J, Kilbourne AM Abstract BACKGROUND: The movement...