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The latest for interventional cardiologists world wide

OpSens Medical | Interventional cardiology in a whole new light
 

Opsens FFR News
TCT Edition

The latest for interventional cardiologists world wide

october 2016
 

Newsletter Highlights

 
 

Case Report

 
 

OptoWire first report: Complex lesion assessment and treatment with no reflow

Excellent fidelity, ease of connection and zero drift

  • Dr Morton Kern and Dr Afnan Tariq, VA Long Beach and University of California Irvine, share their case of pressure measurements during complex PCI over OptoWire Deux as a workhorse tool

Consult the Case Report:

PDF  
 
 

Publications

 
 

Expert recommendations on FFR in Acute Coronary Syndromes (ACS)

Is FFR reliable in NSTEMI? STEMI? Non-culprit and culprit lesions? 

  • In a recent JACC editorial, Drs Fearon, De Bruyne and Pijls review the data to support the role of measuring FFR in ACS

Link to article:

Article  
 
 

Conferences

 
 
 

Transcatheter Cardiovascular Therapeutics (TCT)
Oct 29 - Nov 2, 2016, 

Visit the Opsens booth and joins us for a complimentery breakfast symposium!
 

Visit Opsens at booth #1326
Learn how OptoWire Deux is setting the new standard in pressure guidewire performance and versatility



Drift-Free FFR with a Workhorse Wire: Is it Truly Possible Now?
Join us for a breakfast meeting at TCT 2016
SPONSORED BY OPSENS, INC.

Monday Oct. 31, 2016
Breakfast 6:30 AM, Program 7:00-8:00 AM
Walter E. Washington Convention Center
Room 145A, Lower Level

AGENDA
7:00 am  -  Welcome / review of FFR tools (Morton J. Kern)
7:10 am  -  What makes OptoWire special? - North American Experience  (Olivier F. Bertrand)
7:20 am  -  Oops – my Pd ≠
 my Pa (Bernard De Bruyne)
7:30 am  -  OptoWire - Japanese experience (Hitoshi Matsuo)
7:40 am  -  Roundtable discussion
7:55 am  - Wrap-up / Conclusion
8:00 am  -  Adjourn
 
Space is limited. 

Register for symposium
 
 
 
Request a demonstration of the Optowire at TCT
 
 

TCT FFR highlights by day

Saturday Oct 29

  • ABCs of Interventional Cardiology 2016: An Introductory Course
    Coronary Pathophysiology and FFR
    Sat, Oct 29, 3:30 PM, Room 147, Level 1
Sunday Oct 30
  • Learn the Technique (Case Reviews): Nuts and Bolts of FFR, iFR, and CFR
    Sun, Oct 30, 12:00-1:00 PM, Room 103A, Level 1
  • Learn the Technique (Case Reviews): Management of Calcified Coronary Lesions
    Case Presentations: Intravascular Imaging and Physiologic Assessment Should Be Mandatory When Treating Calcified Lesions
    Sun, Oct 20, 12:30 PM, Room 145A, Level 1
    Management of Calcified Coronary Lesions     
  • Didactic Session: The Left Main and Bifurcation Summit, Part 1: Technique and Cases
    Session I. Anatomical and Physiologic Considerations in Bifurcation Lesions
    Sun, Oct 30, 2:00-2:54 PM, Room 207, Level 2
  • Edited Taped Cases II: Coronary and Peripheral Intervention
    The Physiological Impact of CTO PCI on Donor Vessel Physiology and the Influence of Collateral Regression
    Sun, Oct 30, 3:00PM
    Presentation Theater 4, Exhibit Hall, Level 2
  • Moderated Poster Session: Physiologic Lesion Assessment
    Sun, Oct 30, 3:00-4:00 PM, Moderated Posters and Challenging Cases 2, Exhibit Hall, Level 2
Monday Oct 31
  • Breakfast symposium, sponsored by Opsens
    Drift-free FFR with a Workhorse Wire: Is it Truly Possible Now? 
    Mon, Oct 31, 7:00-8:00 AM, Room 145A
  • Featured Clinical Research: Presentations to the Editors of the Journal of the American College of Cardiology
  • FAME I and FAME II: Predictive Value of FFR After DES Implantation
    Mon, Oct 31, 12:00 PM, Room 152, Level 1
  • Moderated Poster Session: Diabetes and PCI Outcomes
    TCT 262: Clinical Outcomes of Deferred Revascularization Using FFR in Patients With and Without Diabetes Mellitus
    Mon, Oct, 3:30 PM, Moderated Posters and Challenging Cases 2, Exhibit Hall, Level 2
  • Didactic Session: CHIP: Calcified Lesions, Multivessel/Diffuse Disease, Vein Grafts, Shock, and More
    Session II. CHIP A-Z: Technique in Complex and High-risk PCI
           
    Using Intravascular Imaging and Physiology to Guide CHIP Cases: The Essentials
    Mon, Oct 31, 3:38 PM, Room 150, Level 1
  • Partnership Session: CardioVascular Summit TCTAP in Partnership With TCT: Complex PCI (Left Main, Bifurcation, and CTO): The Simpler, the Better
    FFR-Guided Decision Making Is Now Standard
    Mon, Oct 31, 4:25 PM, Room 143B, Level 1
Tues, Nov 1
  • Didactic Session: Optimizing Outcomes With Intravascular Imaging and Physiologic Lesion Assessment, Part I
    Tues Nov 1, 2:00-6:12 PM, Room 150, Level 1
  • Moderated Poster Session: Physiologic Lesion Assessment and Aortic Stenosis
    Tues, Nov 3:00-4:00 PM, Moderated Posters and Challenging Cases 2, Exhibit Hall, Level 2
 
 
 

Stanford coronary physiology conference

  • October 28th, 2016, 8:00 AM - 5:00 PM, Hyatt Regency Washington on Capitol Hill, Washington DC
  • Faculty:  Colin Berry, Morton J. Kern, Nils P. Johnson, Seung-Jung Park, Keith Oldroyd, Habib Samady, Jennifer A. Tremmel
Course director William Fearon and co-directors Nico Pijls and Bernard De Bruyne bring you a full day of CME-accredited education of coronary physiology, focused on FFR.  
 
Register
 
 
 

Expert Corner

 
 
 

Bernard De Bruyne, MD, PhD

Cardiovascular Center, Aalst, Belgium

 
 

Expert Corner: Standardization of FFR measurements and ensuring absence of drift

By agreeing on steps for standardizing FFR measurements we can enhance the uniformity of clinical practice and data interpretation.  A complete document with just such a proposal for FFR standardization can be found in the August issue of the Journal of the American College of Cardiology. This review covers all aspects of acquiring, recording, interpreting, and archiving the pressure tracings for daily practice and for the purpose of clinical research involving a core laboratory.

 
 
 

An important aspect of FFR standardization involves making sure measurements are accurate and not made incorrect by drift. We have listed steps that will help ensure drift is absent or minimal, including proper calibration and equalization.  The importance of these “zeroing” and “equalization” procedures, is to ensure that the two pressure systems “speak the same language”

 
 

Below are tips for how to ensure Pa and Pd pressures are correct to begin with, and how to check if either transducer has drifted during the case. Equalizing the two pressures before measurement, and the documenting the absence of significant Pa or Pd drift immediately after measurement, should be part of every procedure. 

  • Before proceeding to measure pressure across the stenosis:
    • Position the pressure sensor 1 or 2 mm distal to the tip of the guiding catheter
    • Flush the guiding catheter with saline to remove any residual contrast used when positioning the guide
    • With the sensor in this position, check that the two pressures are identical
    • Document by angiography
    • If Pa and Pd are not identical, equalize electronically, using that function of the console
  • After finishing a pressure measurement:
    • Pull back the pressure sensor until again positioned 1 or 2 mm distal to the tip of the guiding catheter
    • At this location, both measured pressures (Pa and Pd) should once again be identicalIn cases of very obvious drift (>3mmHg), re-equalize and repeat pressure measurements  
 In the case of ostial coronary disease, disengage the guiding catheter, and position the pressure sensor in the aorta during equalization.  Care should be taken that the conditions when checking for drift are consistent with the conditions during equalization and during measurement itself.  For example, an introductory needle, if used, should be removed from the Y connector for equalization, for the measurements, and for the final check for the absence of drift.  
 
Recent developments, including the fiberoptic Optowire®, (Opsens Inc,),
make us confident that drift can be eliminated
 
Since the first introduction of coronary pressure wires, drift has been a problem that has been reduced, but not eliminated over the years. For a long time it was accepted as inevitable, making it necessary in cases of very obvious drift for us to re-equalize and repeat measurements.  Some manufacturers of pressure guidewires have endeavored to eliminate drift, and recent developments, including the fiberoptic Optowire®, (Opsens Inc.), make us confident that this goal can be achieved
 
Read the complete document on FFR standardization:
 
 

About Opsens

 
 

Opsens aims to be a key player in FFR

Opsens was established in 2004, and founded on the belief that our innovative technologies will help to improve cardiovascular disease treatment.  We are committed to providing solutions to the unmet medical professional and patient needs of the day.

Our goal is the same as yours: better outcomes.  We work with our clinical partners in delivering forward-thinking technologies and expert solutions providing greater control to physicians with systems that are intuitive to use, with optimal positioning and that improve outcomes for patients. Opsens aims to become a key player in the FFR market, offering OptoWire, an advanced nitinol-based optical pressure guidewire.

Learn more about Opsens:

opsens  
 
 

About OptoWire

 
 

A workhorse interventional guidewire that measures pressure

OptoWire from Opsens provides intra-coronary blood pressure measurements using unique, patented optical pressure guidewire technology.

It is immune to adverse effects related to blood contact, and allows easy and reliable connectivity that leads to reliable FFR measurements in extended conditions of usage. OptoWire is also designed to provide cardiologists with a guidewire that provides optimal performance to navigate coronary arteries and cross blockages with ease and safety.

optowire