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The Latest Updates from Frailty Science

Whether you are a researcher, clinician, student, policy maker, advocate, older adult, or caregiver—we hope you will find something interesting or useful on our site. We aim to provide a gateway to information for those seeking to learn more about frailty, vulnerability and resiliency in older adults. Below are the latest updates to the site.  Please visit for state-of-the-art information on frailty-related science and how it might impact health and wellness for older adults.

Two great new podcasts were posted this month....


Date Published:  November 11, 2021
Episode Number:  8

The eighth episode of the Fighting Frailty Podcast is a special one: our host, Ramana Kolady, introduces an in-depth conversation with Dr. Linda P. Fried on the evolution of frailty science, facilitated by Dr. Jeremy Walston. As a geriatrician, Dr. Fried’s innovative thinking about how frailty develops and manifests led to the landmark publication, “Frailty in Older Adults: Evidence for a Phenotype." The Fighting Frailty Podcast is developed and sponsored by

Date Published:  October 27, 2021
Episode Number:  7

For the seventh episode of the Johns Hopkins Fighting Frailty Podcast, our host Ramana Kolady, an intern with the Frailty Science team at Johns Hopkins, speaks with Dr. Susan Gearhart, Associate Professor of Surgery in Johns Hopkins University School of Medicine, to discuss surgery among older adults and how frailty may play a role during the peri-operative process. Developed and sponsored by

News & Announcements

November 14th is World Diabetes Day
As people with diabetes live longer, there are many geriatric conditions that occur more frequently in people with diabetes compared to those without diabetes, including cognitive impairment, incontinence, falls, and polypharmacy. Continue Reading

Metabolic Dysregulation in Frailty
Metabolic regulation involves the life-sustaining chemical reactions that occur within a living creature on and within the cellular level. When these complex, intertwined biological chemical reactions are no longer well-supported, then accelerated aging may begin to occur in the organism. This process interferes with cellular homeostasis and energy for physiological functions, and can result in metabolic dysregulation, which may present as symptomatic hallmarks of frailty over time: declining weight, declining strength, and declining energy.  Continue Reading

Call for Papers: BMC Geriatrics has announced a call for a collection of papers focused on frailty research: Manuscript categories include: Epidemiology and Measurement; Frailty Biology; Frailty and Clinical Care; and Interdisciplinary Topics. You can read more about this opportunity for advancing the visibility of frailty research here.


Copyright © 2021 Frailty Science, All rights reserved. is funded by the National Institute on Aging, P30-AG021334. ©2021

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