Determination of antibodies against Legionella pneumophila with Euroimmun ELISA and IIFT
Legionella is a bacterial infection of the respiratory tract that presents in two forms: Pontaic fever and Legionnaire's disease. Depending on patient health and treatment onset, lethality sits at around 15%. In untreated individuals this increases to 80%. Legionella bacteria tend to be transmitted through inhalation of water aerosols. The bacteria is found worldwide, and prefers to proliferate in warm water.
Direct detection of the bacterium (in culture, through direct immunofluorescence, or with PCR) is successful only in 5 to 30% of cases - thus, indirect test methods such as ELISA and IIFT are particularly important in a clinical setting.
ELISA is used by laboratories that require a quantifiable, automated, quick result. Euroimmun offer three Legionella ELISA kits, each of which tests for one Ig class.