Haemoglobin interference with HbA1c results
HbA1c is a well-known method of diagnosing diabetes. Common haemoglobin variants have been shown to interfere with HbA1c results from some assay methods. Clinically significant interferences may result in either over- or under-treatment. With several common haemoglobin variants, it is important to know which methods show interference from one or more of these variants.
The Sebia Capillarys 3 Tera and Capillarys 2 Flex-Piercing instruments were two of the assay methods used in this research, and were the only two instruments using capillary electrophoresis for HbA1c measurement. They performed very well in the test, showing NO clinically significant interference from any of the variants detected. Several other HbA1c assay methods showed clinically significant interference, which could adversely affect patient care.
For more information on Sebia product, visit our new website.